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Synthesis of unnatural amino acids and other blocks

[Ala4] - MBP (1 - 11)

Name
[Ala4] - MBP (1 - 11)
Molecular structural formula
Purity
≥95%
CAS Number
125366-42-9
Formula
C49H81N21O17
MW
1236.32
Target
others
Sequence
Ac-Ala-Ser-Gln-Ala-Arg-Pro-Ser-Gln-Arg-His-Gly
Sequence Shortening
Ac-ASQKRPSQRSK
References
[1]. Offner H, et al. Estrogen potentiates treatment with T-cell receptor protein of female mice with experimental encephalomyelitis. J Clin Invest. 2000 May;105(10):1465-72. [2]. Adlard K, et al. Immunoregulation of encephalitogenic MBP-NAc1-11-reactive T cells by CD4+ TCR-specific Tcells involves IL-4, IL-10 and IFN-gamma. Autoimmunity. 1999;31(4):237-48.
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Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP).